A combination of minimally invasive modalities can induce collagen regeneration more quickly and promote the penetration of topical agents, thus promoting skin rejuvenation. In this study, we aimed to investigate the synergistic efficacy of extracellular ...

The extracellular matrix (ECM) is a complex mixture of structural proteins, proteoglycans, and signaling molecules that are essential for tissue integrity and homeostasis. While a number of recent studies have explored the use of decellularized ECM (dECM) ...

BACKGROUND: Noninvasive facial-rejuvenation devices, such as nonablative radiofrequency (RF) and laser-assisted technology, are increasingly replacing higher-risk surgeries for face and body skin laxity. OBJECTIVE: We sought to review published information ...

As people live longer and stay healthier, many want to look as youthful as they feel. The general population continues to explore nonsurgical options to augment and possibly delay traditional rhytidectomy. Herein, we present a unique nonsurgical option to enhance our current modalities of neuromodulators and fillers commonly used on the face and neck. In addition, we discuss the ideal application of this technology including treatment times and intervals between treatments.